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The 60-37 vote clears away procedural hurdles for legislation that would allow the president to negotiate trade pacts and then put them on a so-called fast track through Congress.
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In a close vote, the House approved fast-track authority, but the fate of the trade measure is still to be determined.
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Intra-party turmoil could spill over into the next election, with labor groups threatening primaries against members — even those who sit in swing districts — who sided with the president.
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The Republican House Ways and Means chairman explains to Steve Inskeep why he supports the Trans-Pacific Partnership deal, which is now working its way — in fits and starts — through Congress.
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In an extremely polarized Congress, last week's trade vote yielded an unusually haphazard-looking mix of votes. Here's a breakdown of how the House voted and why it matters.
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Labor unions argue it's yet another deal that will erode American jobs and benefit corporations. But labor specialists say there's a flip side: Companies more engaged in global trade pay higher wages.