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The company says a low-dose version of its vaccine triggers an immune response in children ages 6 months to less than 6 years equivalent to what has protected older children and adults.
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No deaths were reported in tests, and there were no signs of myocarditis, or heart inflammation, as a side effect.
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Now, both the Pfizer and the Moderna booster shots can be given five months after the second dose of vaccine — down from six months.
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Moderna said its current FDA-authorized 50-microgram booster shot increased antibody levels against omicron 37-fold compared to pre-booster levels.
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The Moderna vaccine's ability to shield against infection drops sharply when tested on the omicron variant. But getting a booster pumps the protection back up again, new research suggests.
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Moderna says the FDA is looking into reports of a rare side effect — myocarditis, or the inflammation of the heart muscle — in those who've gotten the shot.
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Moderna says a study in kids 6 to 11 found two doses of the company's COVID-19 vaccine given 28 days apart produced a strong antibody response.
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CDC Director Rochelle Walensky also endorsed a mix-and-match approach to boosters that would be flexible for patients and health care providers.
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It's the first step in an audacious plan to solve vaccine inequity by setting up the manufacturing of mRNA vaccines across low-resource countries.
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The recommendation applies to people 65 years and older, those 18 to 64 who are at high risk of severe COVID and those whose work or institutional exposure puts them at high COVID risk.